Association between lipoprotein(a) and atherosclerosis with different diabetic status: a cross-sectional study in a Chinese population

In patients with chest pain and DM without cardiovascular disease (CVD), Lp(a) level was significantly associated with subclinical atherosclerosis and had a synergistic effect with DM. Notably, lower Lp(a) levels in patients with DM may lead to an additional subclinical atherosclerosis risk, whereas prediabetes does not show the same association. Therefore, these findings highlight the importance of formulating early preventive strategies for subclinical atherosclerosis based on Lp(a) levels and diabetic status.

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Publication Details

Journal
Cardiovascular Diagnosis and Therapy
Published
2025-02-01
DOI
https://doi.org/10.21037/cdt-24-410
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between lipoprotein(a) and atherosclerosis with different diabetic status: a cross-sectional study in a Chinese population

MA Kang-hua, Min Zhang, Yue Luo, Min Mao et al.
Cardiovascular Diagnosis and Therapy
Lipoproteins and Cardiovascular Health
article

Association between lipoprotein(a) and atherosclerosis with different diabetic status: a cross-sectional study in a Chinese population

MA Kang-hua, Min Zhang, Yue Luo, Min Mao, Guoli Yang, Qian Dong, Ping Tang, Bao Feng Yang
article en

Abstract

In patients with chest pain and DM without cardiovascular disease (CVD), Lp(a) level was significantly associated with subclinical atherosclerosis and had a synergistic effect with DM. Notably, lower Lp(a) levels in patients with DM may lead to an additional subclinical atherosclerosis risk, whereas prediabetes does not show the same association. Therefore, these findings highlight the importance of formulating early preventive strategies for subclinical atherosclerosis based on Lp(a) levels and diabetic status.

Cardiovascular Diagnosis and TherapyVol. 15(1)
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 94%
Lipoproteins and Cardiovascular Health
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