Myositis of pterygoid muscles and superior ophthalmic vein and cavernous sinus thrombosis in active Crohn’s disease undergoing ustekinumab treatment: a case report and literature review

Our report accounts for the second patient described in literature with myositis associated with CD while being treated with UST. The causal factor remains speculative, as both active CD and UST treatment may contribute to this complication. Sharing clinical experiences and reporting possible adverse events to regulatory agencies can enhance our understanding of rare complications and improve patient outcomes by providing therapeutic strategies.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-02-26
DOI
https://doi.org/10.3389/fphar.2025.1544466
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Myositis of pterygoid muscles and superior ophthalmic vein and cavernous sinus thrombosis in active Crohn’s disease undergoing ustekinumab treatment: a case report and literature review

Dries Govaerts, Ilse Mombaerts, Sara Kaut, Ilse Hoffman et al.
Frontiers in Pharmacology
IgG4-Related and Inflammatory Diseases
article

Myositis of pterygoid muscles and superior ophthalmic vein and cavernous sinus thrombosis in active Crohn’s disease undergoing ustekinumab treatment: a case report and literature review

Dries Govaerts, Ilse Mombaerts, Sara Kaut, Ilse Hoffman, Aaron De Poortere, Karen van Hoeve, Robin Willaert, Ryan M. Winters
article en

Abstract

Our report accounts for the second patient described in literature with myositis associated with CD while being treated with UST. The causal factor remains speculative, as both active CD and UST treatment may contribute to this complication. Sharing clinical experiences and reporting possible adverse events to regulatory agencies can enhance our understanding of rare complications and improve patient outcomes by providing therapeutic strategies.

Frontiers in PharmacologyVol. 16
KU Leuven (BE)
Openalex Percentile: Top 94%
IgG4-Related and Inflammatory Diseases
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