Characterization and genome analysis of novel Klebsiella pneumoniae phage vbKpUKJ_2 isolated from hospital sewage water
vbKpUKJ_2 shows promising therapeutic potential against MDR K. pneumoniae. Its stability, absence of resistance genes, and rapid lytic cycle highlight its suitability for inclusion in phage therapy protocols, particularly as part of combination therapies targeting MDR infections.
Authors
- Sándor Nietzsche (ORCID: https://orcid.org/0000-0002-1198-6464)
- Kamran A. Mirza (ORCID: https://orcid.org/0009-0008-1943-768X)
- Mike Marquet (ORCID: https://orcid.org/0000-0003-4344-8289)
- Mathias Wilhelm Pletz (ORCID: https://orcid.org/0000-0001-8157-2753)
- Tinatini Tchatchiashvili (ORCID: https://orcid.org/0000-0002-0281-1208)
- Oliwia Makarewicz (ORCID: https://orcid.org/0000-0002-4404-1862)
Institutions
- Leibniz Institute of Photonic Technology (DE)
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1186/s12866-025-03813-y
- Citations
- 7
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 12.01
Funders
- Bundesministerium für Bildung und Forschung