Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease

PPBP, CXCL1, and RSAD2 are key genes closely related to the occurrence and development processes between AF and CKD. Among them, the CXCLs/CXCR signaling pathway play a crucial role in the development processes of the two diseases likely. In addition, FOXC1, FOXL1, and GATA2 may be potential therapeutic targets for AF combined with CKD, and the development of the diseases is closely related to immune cell infiltration.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-02-26
DOI
https://doi.org/10.3389/fcvm.2025.1521722
Primary Topic
Atherosclerosis and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease

Guo‐Xiong Deng, Jinliang Teng
Frontiers in Cardiovascular Medicine
Atherosclerosis and Cardiovascular Diseases
article

Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease

Guo‐Xiong Deng, Jinliang Teng
article en

Abstract

PPBP, CXCL1, and RSAD2 are key genes closely related to the occurrence and development processes between AF and CKD. Among them, the CXCLs/CXCR signaling pathway play a crucial role in the development processes of the two diseases likely. In addition, FOXC1, FOXL1, and GATA2 may be potential therapeutic targets for AF combined with CKD, and the development of the diseases is closely related to immune cell infiltration.

Frontiers in Cardiovascular MedicineVol. 12
Guangxi Medical University (CN), First People's Hospital of Nanning (CN)
Openalex Percentile: Top 96%
Atherosclerosis and Cardiovascular Diseases
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