Bacillus subtilis spores displaying Toxoplasma gondii GRA12 induce immunity against acute toxoplasmosis
Mice immunized with rBS-GRA12 exhibited higher levels of cellular, humoral, and mucosal immune responses than control mice. These results provide a new perspective for the development of <i>T. gondii</i> vaccines.
Authors
- Shi-yi Ye
- Lili Hao (ORCID: https://orcid.org/0000-0002-9243-1910)
- Yuan Fu (ORCID: https://orcid.org/0000-0002-0167-642X)
- Lihua Xu (ORCID: https://orcid.org/0000-0002-2237-9336)
- Hongchao Sun
- Xin Hua Zhou (ORCID: https://orcid.org/0000-0002-5580-7907)
- Xin Liu (ORCID: https://orcid.org/0000-0002-2173-4201)
- Bin Yu (ORCID: https://orcid.org/0000-0002-8827-1256)
- Fei Su (ORCID: https://orcid.org/0000-0003-4737-4651)
- Wei Zhou (ORCID: https://orcid.org/0000-0003-2787-5045)
- Junxing Li (ORCID: https://orcid.org/0000-0002-1365-2441)
- Tuanyuan Shi
- Zhijin Zhou
- Yuan XiuFang
Institutions
- ZheJiang Academy of Agricultural Sciences (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
- Southwest Minzu University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1457560
- Citations
- 1
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.05