Virological response and predictive factors for antiviral treatment in chronic HBV-related liver disease with low ALT and high HBV DNA

The NG group has lower CVR, but the high-normal ALT subgroup performs similarly to MAG. High HBV DNA and low ALT significantly reduce CVR. Key adverse predictors include low ALT, high HBV DNA, HBeAg positivity, low APRI, and suboptimal viral reduction at 12 weeks.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-02-26
DOI
https://doi.org/10.3389/fimmu.2025.1556547
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Virological response and predictive factors for antiviral treatment in chronic HBV-related liver disease with low ALT and high HBV DNA

Huichun Xing, Danni Li, L C Weng, Lei Ma
Frontiers in Immunology
Hepatitis B Virus Studies
article

Virological response and predictive factors for antiviral treatment in chronic HBV-related liver disease with low ALT and high HBV DNA

Huichun Xing, Danni Li, L C Weng, Lei Ma
article en

Abstract

The NG group has lower CVR, but the high-normal ALT subgroup performs similarly to MAG. High HBV DNA and low ALT significantly reduce CVR. Key adverse predictors include low ALT, high HBV DNA, HBeAg positivity, low APRI, and suboptimal viral reduction at 12 weeks.

Frontiers in ImmunologyVol. 16
Capital Medical University (CN), Peking University (CN), Beijing Ditan Hospital (CN)
Openalex Percentile: Top 94%
Hepatitis B Virus Studies
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