Clinical Characteristics and Visual Prognostic Biomarkers in Pericentral Retinitis Pigmentosa: A Study in a South Korean Cohort
South Korean patients with pericentral RP exhibited a milder phenotype compared to typical RP patients reported in previous studies. Genetic analysis revealed heterogeneity, with mutations in some genes commonly associated with milder forms of RP. Male sex and prolonged b-wave latency on dark-adapted 0.01 electroretinogram were significant biomarkers for predicting rapid visual acuity decline. Monitoring initial b-wave latency is important for predicting visual decline, particularly in male patients with pericentral RP.
Authors
- Su Ho Bae
- Un Chul Park (ORCID: https://orcid.org/0000-0002-3588-4497)
- Seung Woo Choi (ORCID: https://orcid.org/0000-0002-4189-8756)
- Chang Ki Yoon (ORCID: https://orcid.org/0000-0003-4637-8044)
- Eun Kyoung Lee (ORCID: https://orcid.org/0000-0002-2952-1286)
- Kyu Hyung Park
Institutions
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Korean Journal of Ophthalmology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3341/kjo.2024.0097
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00