The association between blood sodium levels and survival in patients treated with immune checkpoint inhibitors
This study highlights that ICI-treated patients with higher sodium levels had significantly better OS, PFS, and anti-tumor responses. Baseline serum sodium levels could be cost-effective and valuable predictive biomarker for ICIs across diverse tumor types and ICI agents.
Authors
- Zafer Arık (ORCID: https://orcid.org/0000-0002-0598-389X)
- Mine Durukan (ORCID: https://orcid.org/0000-0002-5452-3208)
- Taha Koray Şahin (ORCID: https://orcid.org/0000-0002-3590-0426)
- Yunus Kaygusuz (ORCID: https://orcid.org/0000-0002-3894-7203)
- Mustafa Erman (ORCID: https://orcid.org/0000-0001-5884-4669)
- Sercan Aksoy (ORCID: https://orcid.org/0000-0003-4984-1049)
- Gözde Kavgacı (ORCID: https://orcid.org/0000-0001-6960-2024)
- Şuayib Yalçın (ORCID: https://orcid.org/0000-0001-7850-6798)
- Deniz Can Güven (ORCID: https://orcid.org/0000-0002-6924-9467)
- Omer Dizdar
Institutions
- Cancer Institute (WIA) (IN)
- Hacettepe University Hospital (TR)
- Hacettepe University (TR)
Publication Details
- Journal
- Expert Review of Molecular Diagnostics
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1080/14737159.2025.2472946
- Citations
- 2
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.04