Gentiopicroside targeting AKT1 activates HIF-1α/VEGF axis promoting diabetic ulcer wound healing
GSP target binding to AKT1 accelerates DU wound healing via the regulation of HIF-1α/VEGF axis.
Authors
- Xinxia Wang (ORCID: https://orcid.org/0000-0002-2328-7003)
- Mingyan Liu (ORCID: https://orcid.org/0000-0003-2352-8425)
- Liu L (ORCID: https://orcid.org/0000-0001-9234-457X)
- Zheng Pan (ORCID: https://orcid.org/0000-0002-9727-7975)
- Yao Wu (ORCID: https://orcid.org/0000-0002-4524-0572)
- Jianguo Sun (ORCID: https://orcid.org/0000-0003-1575-0202)
Institutions
- Second Military Medical University (CN)
- First Hospital of Shijiazhuang (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3389/fphar.2025.1506499
- Citations
- 5
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.13