Unraveling the impact of laser refractive surgery on corneal ectasia: an in silico study
While the three refractive procedures showed different behaviors in terms of mechanical changes affecting the cornea, from an optical perspective, as the pathology severity worsened, none of the surgeries caused a worsening in the cone's severity with respect to pre-surgical pathological conditions. This result suggests that surgeries may have a limited role in causing post-surgical ectasia, as it seems more plausible that they accelerate the progression of an underlying pathological condition. Among the three procedures, PRK was found to be the least invasive treatment from a mechanical perspective, while SMILE showed the greatest impact on the posterior surface, suggesting a potential long-term risk for ectasia progression.
Authors
- Benedetta Fantaci
- Begoña Calvo (ORCID: https://orcid.org/0000-0001-9713-1813)
- José Félix Rodríguez Matas
- Vittoria Squartecchia
- Lucia Vavassori
Institutions
- Universidad de Zaragoza (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Politecnico di Milano (IT)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3389/fbioe.2025.1548539
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Horizon 2020