Unraveling the impact of laser refractive surgery on corneal ectasia: an in silico study

While the three refractive procedures showed different behaviors in terms of mechanical changes affecting the cornea, from an optical perspective, as the pathology severity worsened, none of the surgeries caused a worsening in the cone's severity with respect to pre-surgical pathological conditions. This result suggests that surgeries may have a limited role in causing post-surgical ectasia, as it seems more plausible that they accelerate the progression of an underlying pathological condition. Among the three procedures, PRK was found to be the least invasive treatment from a mechanical perspective, while SMILE showed the greatest impact on the posterior surface, suggesting a potential long-term risk for ectasia progression.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2025-02-26
DOI
https://doi.org/10.3389/fbioe.2025.1548539
Citations
1
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
1.36

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article

Unraveling the impact of laser refractive surgery on corneal ectasia: an in silico study

Benedetta Fantaci, Begoña Calvo, José Félix Rodríguez Matas, Vittoria Squartecchia et al.
1 citations
Frontiers in Bioengineering and Biotechnology
Corneal surgery and disorders
1.36
article

Unraveling the impact of laser refractive surgery on corneal ectasia: an in silico study

Benedetta Fantaci, Begoña Calvo, José Félix Rodríguez Matas, Vittoria Squartecchia, Lucia Vavassori
article en
1 citations

Abstract

While the three refractive procedures showed different behaviors in terms of mechanical changes affecting the cornea, from an optical perspective, as the pathology severity worsened, none of the surgeries caused a worsening in the cone's severity with respect to pre-surgical pathological conditions. This result suggests that surgeries may have a limited role in causing post-surgical ectasia, as it seems more plausible that they accelerate the progression of an underlying pathological condition. Among the three procedures, PRK was found to be the least invasive treatment from a mechanical perspective, while SMILE showed the greatest impact on the posterior surface, suggesting a potential long-term risk for ectasia progression.

Frontiers in Bioengineering and BiotechnologyVol. 13
Universidad de Zaragoza (ES), Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES), Politecnico di Milano (IT)
Horizon 2020
Openalex Percentile: Top 23%
Corneal surgery and disorders
1.36
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