Acetate and propionate vs. iTBS as a novel method for cognitive dysfunction and anxiety symptoms in delayed encephalopathy after acute carbon monoxide poisoning rat
These results indicate that both iTBS and SCFA solutions consisting of acetate and propionate produced good effects on DEACMP rats by regulating inflammation levels in the hippocampus, and acetate/propionate-GPR41/GPR43-IL-1β/IL-6/TNF-α-dopamine/norepinephrine may be a potential pathway in SCFAs for the treatment of DEACMP.
Authors
- Lehua Yu (ORCID: https://orcid.org/0000-0003-4852-907X)
- Tianyu Meng
- Xin Zhang (ORCID: https://orcid.org/0000-0002-5927-9283)
- Jili Zhao (ORCID: https://orcid.org/0000-0002-7482-3400)
- Hui Xue (ORCID: https://orcid.org/0000-0002-7578-0289)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Baotou Central Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3389/fphar.2025.1520988
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.00