Establishment and validation of a dual qPCR method for the detection of carbapenem-resistant Acinetobacter baumannii in bloodstream infections
The qPCR method established in this study has strong specificity, wide linear range, good repeatability, and a lower LOD than PCR (Non-fluorescence quantification). The method provides new technical support for the early clinical diagnosis of CRAB in BSIs.
Authors
- Xiaoxia Kou (ORCID: https://orcid.org/0000-0002-7339-7374)
- Ze Liu (ORCID: https://orcid.org/0000-0002-9906-5351)
- Yu Lin
- Chushi Guan
- Baoqing Sun
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Kingmed Diagnostics (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3389/fcimb.2025.1490528
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Ministry of Education
- Department of Education of Guangdong Province