Phosphorylated alpha-synuclein distribution in the colonic enteric nervous system of patients with diverticular disease
P-aSyn presence in colonic tissue did not significantly differ between DD patients and controls, suggesting that DD-related inflammation does not notably affect P-aSyn expression. Further research is warranted to explore aSyn roles within the enteric nervous system in intestinal inflammatory disorders and their relation with neurodegenerative diseases.
Authors
- Florian Richter
- Thilo Wedel (ORCID: https://orcid.org/0000-0002-8146-2711)
- François Cossais (ORCID: https://orcid.org/0000-0001-8043-296X)
- Martina Böttner
- Marie Christin Hörnke
- Katja Schröder (ORCID: https://orcid.org/0000-0003-1158-2598)
- Jan-Hendrik Egberts (ORCID: https://orcid.org/0000-0003-3994-8897)
- Ralph Lucius
Institutions
- Christian-Albrechts-Universität zu Kiel (DE)
- University Hospital Schleswig-Holstein (DE)
- Israelitisches Krankenhaus (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.ibneur.2025.02.009
- Citations
- 2
- Primary Topic
- Diverticular Disease and Complications
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Faculty of Medicine, McGill University
- Christian-Albrechts-Universität zu Kiel