Exploratory analyses of the associations between Ki-67 expression, lymph node metastasis, and prognosis in patients with esophageal squamous cell cancer
High Ki-67 protein expression is associated with poor prognosis in ESCC. Increased Ki-67 expression significantly increases the risk of LNM, VI, and PI in ESCC, and thus may serve as an indication for adjuvant therapy in ESCC management.
Authors
- Bifen Huang
- Ying Chen (ORCID: https://orcid.org/0000-0002-8884-3138)
- Li-hua Xiao (ORCID: https://orcid.org/0009-0008-3601-9201)
- Jianqing Zheng
- Min Wu (ORCID: https://orcid.org/0000-0002-3865-3731)
- Bingwei Zeng
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-02-26
- DOI
- https://doi.org/10.7717/peerj.19062
- Citations
- 2
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Natural Science Foundation of Fujian Province
- Fujian Provincial Health Technology Project