Identification and Experimental Verification of Potential Immune Cell-Associated Gene Biomarkers in Human Intervertebral Disc Degeneration
This study identified ASAP1-IT1, IKZF2, and KLHL14 as the key signature genes of IDD. These key hub genes may serve as potential therapeutic targets for IDD.
Authors
- Peng-Cheng Chu (ORCID: https://orcid.org/0000-0001-7311-9684)
- Yaning Zhang (ORCID: https://orcid.org/0000-0001-5763-298X)
- Da-chuan Liang
- Bin Li (ORCID: https://orcid.org/0000-0001-8516-9953)
- Xiangyu Wang (ORCID: https://orcid.org/0009-0009-6545-7443)
- Pingping Zhang (ORCID: https://orcid.org/0000-0003-3212-1707)
- Hong Yu (ORCID: https://orcid.org/0000-0002-6819-6607)
- Lili Huang (ORCID: https://orcid.org/0000-0002-4486-3532)
- Hao Zou (ORCID: https://orcid.org/0000-0002-3208-0522)
- Jie Lu (ORCID: https://orcid.org/0000-0003-1503-3801)
- Weihan Shi
Institutions
- Chinese PLA General Hospital (CN)
- The People's Hospital of LinXia (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jpr.s505859
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00