ChromInst: a multicentre evaluation of robustness in aneuploidy and structural rearrangement testing
ChromInst-based PGT-A/-SR could accommodate operational variations among different clinical centres, ensuring accurate results through robust and stable detection performance. Prior to PGT-A/-SR, more trustworthy data could be provided to support the genetic counselling.
Authors
- Yao He (ORCID: https://orcid.org/0000-0002-7165-4517)
- Keya Tong
- Dongyun Liu (ORCID: https://orcid.org/0000-0001-9852-8847)
- Linli Hu (ORCID: https://orcid.org/0000-0001-9069-2466)
- Yifan Zhou (ORCID: https://orcid.org/0000-0002-9836-6355)
- Haixia Jin (ORCID: https://orcid.org/0000-0003-0116-9070)
- Yingpu Sun (ORCID: https://orcid.org/0000-0003-3783-6509)
- Shanjun Dai (ORCID: https://orcid.org/0000-0002-3000-3603)
- Dunmei Zhao
- Wenbin Niu (ORCID: https://orcid.org/0000-0001-5507-1592)
- Guidong Yao (ORCID: https://orcid.org/0000-0002-7174-9989)
- Haiyan Bai
- Yaxin Yao
- Fenghua Liu (ORCID: https://orcid.org/0000-0002-3860-9466)
- Lei Jin (ORCID: https://orcid.org/0000-0001-6924-2364)
- Dun Liu (ORCID: https://orcid.org/0000-0003-1266-8801)
- Senlin Shi (ORCID: https://orcid.org/0000-0002-4814-1510)
- Li Wu (ORCID: https://orcid.org/0009-0009-7680-616X)
- Xiqian Zhang (ORCID: https://orcid.org/0009-0001-5338-8884)
- Xue Xia
- Sijia Lu
- Tian Li (ORCID: https://orcid.org/0000-0003-2548-5166)
Institutions
- Northwest Women's and Children's Hospital (CN)
- Sinotech Genomics (China) (CN)
- Guangdong Province Women and Children Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1186/s12967-025-06242-7
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49