Extracellular Matrix Proteins Improve Risk Prediction in Patients Undergoing Transcatheter Aortic Valve Replacement
Circulating TIMP-1 is an independent predictor of reduced 2-year overall survival in patients undergoing TAVR. Combined with high-sensitivity cardiac troponin T, circulating TIMP-1 should be incorporated into risk stratification to identify patients undergoing TAVR who are at a higher risk of death.
Authors
- David M. Leistner (ORCID: https://orcid.org/0000-0002-4351-420X)
- Stefanie Dimmeler (ORCID: https://orcid.org/0000-0002-1045-2436)
- Badder Kattih (ORCID: https://orcid.org/0000-0003-1324-5536)
- Lukas Zanders (ORCID: https://orcid.org/0000-0003-0488-6243)
- Silvia Mas‐Peiró (ORCID: https://orcid.org/0000-0002-3828-8180)
- Tina Rasper
- Graziella Pergola
- Felicitas Boeckling
- Mariuca Vasa‐Nicotera (ORCID: https://orcid.org/0000-0002-6794-4941)
- Sebastian Cremer (ORCID: https://orcid.org/0000-0002-6409-9279)
Institutions
- Goethe University Frankfurt (DE)
- Goethe-Institute United Kingdom (GB)
- Cardiovascular Center Frankfurt (DE)
- German Centre for Cardiovascular Research (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1161/jaha.124.037296
- Citations
- 5
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.94