Molecular Diffusion and Optical Properties of Implantable Collagen Materials
The effects of optical clearing of implantable collagen materials were studied using optical clearing agents (OCAs) based on aqueous glucose solutions of various concentrations. By measuring the kinetics of the collimated transmission spectra, the diffusion <i>D</i> and permeability <i>P</i> coefficients of the OCAs of collagen materials were determined as <i>D</i> = (0.22 ± 0.05) × 10<sup>-6</sup> to (1.41 ± 0.05) × 10<sup>-6</sup> cm<sup>2</sup>/c and <i>P</i> = (0.55 ± 0.04) × 10<sup>-4</sup> to (1.77 ± 0.07) × 10<sup>-4</sup> cm/c. Studies with optical coherence tomography (OCT) confirmed that each of the OCAs used had an effect on the optical properties of collagen materials, and allowed us to quantify the group refractive indices of the collagen of various samples, which turned out to be in the range from <i>n</i><sub>c</sub> = 1.476 to <i>n</i><sub>c</sub> = 1.579.
Authors
- Daria K. Tuchina (ORCID: https://orcid.org/0000-0003-0203-4979)
- Valery Victorovich Tuchin (ORCID: https://orcid.org/0000-0001-7479-2694)
- Peter S. Timashev (ORCID: https://orcid.org/0000-0001-7773-2435)
- Sofya V. Atsigeida
Institutions
- Saratov State University (RU)
- Sechenov University (RU)
- National Research Tomsk State University (RU)
- Institute of Physics (RU)
- Institute of Precision Mechanics and Control (RU)
Publication Details
- Journal
- Materials
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3390/ma18051035
- Citations
- 1
- Primary Topic
- Electrospun Nanofibers in Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.60
Funders
- Russian Science Foundation