Real-time PCR and immunohistochemistry detection of Wolbachia in adult Dirofilaria immitis from dogs treated with doxycycline and ivermectin
All DOXY dosages can be considered effective in reducing Wolbachia on both tested dates (30 and 60 days). On the basis of the further reduction of Wolbachia levels in adult D. immitis, the 1-month rest period in the AHS heartworm treatment guidelines is beneficial. Wolbachia can still be detected on day 60 in all dosage groups.
Authors
- Crystal Fricks
- Utami DiCosty
- Kaori Sakamoto (ORCID: https://orcid.org/0000-0003-0592-6403)
- Andrew R. Moorhead (ORCID: https://orcid.org/0000-0002-6473-3743)
- Michael T. Dzimianski
- Carmel Nelson
- Abdelmoneim Mansour
- Scott McCall
- Christopher C. Evans (ORCID: https://orcid.org/0000-0003-2762-3171)
- Yi Chu (ORCID: https://orcid.org/0000-0001-7260-1639)
- John W. McCall
Institutions
- North Carolina State University (US)
- University of Georgia (US)
- The Schwarzman Animal Medical Center (US)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1186/s13071-025-06720-3
- Citations
- 1
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.40