A Method for Polyp Segmentation Through U-Net Network

Early detection of colorectal polyps through endoscopic colonoscopy is crucial in reducing colorectal cancer mortality. While automated polyp segmentation has been explored to enhance detection accuracy and efficiency, challenges remain in achieving precise boundary delineation, particularly for small or flat polyps. In this work, we propose a novel U-Net-based segmentation framework specifically optimized for real-world endoscopic colonoscopy data. Unlike conventional approaches, our method leverages high-resolution frames with pixel-level ground-truth annotations to achieve superior segmentation performance. The U-Net architecture, with its symmetric encoder-decoder design and skip connections, is further adapted to enhance both high-level contextual understanding and fine-grained detail preservation. Our model has been rigorously evaluated on a real-world dataset, demonstrating state-of-the-art accuracy in polyp boundary segmentation, even in challenging cases. By improving detection consistency and reducing observer variability, our approach provides a robust tool to support gastroenterologists in clinical decision-making. Beyond real-time clinical applications, this work contributes to advancing automated and standardized polyp detection, paving the way for more reliable AI-assisted endoscopic analysis.

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Publication Details

Journal
Bioengineering
Published
2025-02-26
DOI
https://doi.org/10.3390/bioengineering12030236
Citations
4
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
4.18
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article

A Method for Polyp Segmentation Through U-Net Network

Francesco Mercaldo, Mario Cesarelli, Antonella Santone
4 citations
Bioengineering
Colorectal Cancer Screening and Detection
4.18
article

A Method for Polyp Segmentation Through U-Net Network

Francesco Mercaldo, Mario Cesarelli, Antonella Santone
article en
4 citations

Abstract

Early detection of colorectal polyps through endoscopic colonoscopy is crucial in reducing colorectal cancer mortality. While automated polyp segmentation has been explored to enhance detection accuracy and efficiency, challenges remain in achieving precise boundary delineation, particularly for small or flat polyps. In this work, we propose a novel U-Net-based segmentation framework specifically optimized for real-world endoscopic colonoscopy data. Unlike conventional approaches, our method leverages high-resolution frames with pixel-level ground-truth annotations to achieve superior segmentation performance. The U-Net architecture, with its symmetric encoder-decoder design and skip connections, is further adapted to enhance both high-level contextual understanding and fine-grained detail preservation. Our model has been rigorously evaluated on a real-world dataset, demonstrating state-of-the-art accuracy in polyp boundary segmentation, even in challenging cases. By improving detection consistency and reducing observer variability, our approach provides a robust tool to support gastroenterologists in clinical decision-making. Beyond real-time clinical applications, this work contributes to advancing automated and standardized polyp detection, paving the way for more reliable AI-assisted endoscopic analysis.

BioengineeringVol. 12(3)
University of Molise (IT), University of Sannio (IT)
Good health and well-being
Openalex Percentile: Top 6%
Colorectal Cancer Screening and Detection
4.18
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A Method for Polyp Segmentation Through U-Net Network — Francesco Mercaldo, Mario Cesarelli, et al. · Bioengineering (2025) | TGRS Research Map | TGRS