A Pelvic Mass in a Young Patient With Crohn's Disease

Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.

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Publication Details

Journal
ACG Case Reports Journal
Published
2025-02-26
DOI
https://doi.org/10.14309/crj.0000000000001627
Primary Topic
Viral-associated cancers and disorders
Type
article
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article

A Pelvic Mass in a Young Patient With Crohn's Disease

Frida Rosenblum, Aishwarya Ravindran, Frederick Weber, Charles D. Evers
ACG Case Reports Journal
Viral-associated cancers and disorders
article

A Pelvic Mass in a Young Patient With Crohn's Disease

Frida Rosenblum, Aishwarya Ravindran, Frederick Weber, Charles D. Evers
article en

Abstract

Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.

ACG Case Reports JournalVol. 12(3)
University of Alabama at Birmingham (US)
Life in Land
Openalex Percentile: Top 95%
Viral-associated cancers and disorders
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A Pelvic Mass in a Young Patient With Crohn's Disease — Frida Rosenblum, Aishwarya Ravindran, et al. · ACG Case Reports Journal (2025) | TGRS Research Map | TGRS