Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis
Human-derived immunoglobulin preparations may ameliorate sepsis-related organ dysfunction partially through autophagy-related mechanisms. In the early stage of treatment, enhancement of autophagy in the kidney appears to be associated with C5aR expression.
Authors
- İlkay Anaklı (ORCID: https://orcid.org/0000-0002-0403-4860)
- Canan Ulusoy (ORCID: https://orcid.org/0000-0002-5599-4917)
- Figen Esen (ORCID: https://orcid.org/0000-0003-4419-4903)
- Erdem Tüzün (ORCID: https://orcid.org/0000-0002-4483-0394)
- Vuslat Yılmaz (ORCID: https://orcid.org/0000-0002-4809-2966)
- Gizem Koral (ORCID: https://orcid.org/0000-0001-9484-9440)
- Mert Canbaz (ORCID: https://orcid.org/0000-0003-3489-6944)
- Özlem Polat (ORCID: https://orcid.org/0000-0003-3806-5574)
- Günseli Orhun (ORCID: https://orcid.org/0000-0003-0173-3604)
- Perihan Ergin Özcan (ORCID: https://orcid.org/0000-0001-7986-4984)
Institutions
- Istanbul University (TR)
Publication Details
- Journal
- In Vivo
- Published
- 2025-02-26
- DOI
- https://doi.org/10.21873/invivo.13883
- Citations
- 1
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 1.32