Analysis of Risedronate Analog on Extraction Socket Healing in Mice
High bone affinity without potent inhibition of bone resorption does not induce MRONJ-like lesions in mice. These findings suggest that the potent anti-resorptive activity of N-BPs is a key factor in MRONJ development, highlighting the importance of bone turnover suppression in the pathogenesis of this condition.
Authors
- Masato Kaku (ORCID: https://orcid.org/0000-0002-3878-749X)
- Hiroki Nikawa
- Yuichi Mine (ORCID: https://orcid.org/0000-0002-7057-1955)
- Atsushi Ueda (ORCID: https://orcid.org/0000-0002-7659-8964)
- Takeshi MURAYAMA
- Mizuho SANO
- Moeka KASAGAWA
- YUKINAGA KUROKUI
Institutions
- Hiroshima University (JP)
Publication Details
- Journal
- In Vivo
- Published
- 2025-02-26
- DOI
- https://doi.org/10.21873/invivo.13870
- Citations
- 2
- Primary Topic
- Biopolymer Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.61