International Validation and Refinement of Oncological Borderline Resectability Criteria for Hepatocellular Carcinoma Using Tumor Burden Score to Predict Survival
The TBS-BR composite model, integrating tumor morphology (TBS), tumor biology (log AFP), overall physical status (ASA class), and liver function (ALBI score) demonstrated superior predictive accuracy for OS compared with the original BR and Barcelona Clinic Liver Cancer classifications.
Authors
- Luca Aldrighetti (ORCID: https://orcid.org/0000-0001-7729-2468)
- Ana Gleisner (ORCID: https://orcid.org/0000-0002-5040-4105)
- Thomas J. Hugh (ORCID: https://orcid.org/0000-0001-6690-342X)
- Irinel Popescu (ORCID: https://orcid.org/0000-0002-2897-1170)
- Sara Oliveira (ORCID: https://orcid.org/0000-0003-2322-6531)
- Andrea Ruzzenente
- Vincent Lam (ORCID: https://orcid.org/0000-0001-5566-4769)
- Nazim Bhimani (ORCID: https://orcid.org/0000-0003-3995-4285)
- Jun Kawashima (ORCID: https://orcid.org/0000-0003-1072-0776)
- Federico Aucejo (ORCID: https://orcid.org/0000-0001-7841-229X)
- Minoru Kitago
- Timothy Michael Pawlik (ORCID: https://orcid.org/0000-0002-7994-9870)
- Yuki Imaoka (ORCID: https://orcid.org/0000-0003-0882-5341)
- George A. Poultsides (ORCID: https://orcid.org/0000-0002-7584-0405)
- Miho Akabane (ORCID: https://orcid.org/0000-0002-6705-5730)
- Selamawit Woldesenbet (ORCID: https://orcid.org/0000-0002-5023-3561)
- Itaru Endo
- Hugo P. Marques (ORCID: https://orcid.org/0000-0003-3540-0488)
- Feng Shen (ORCID: https://orcid.org/0000-0001-8119-887X)
- Jorge Balaia
- Guillaume Martel
- Abdullah Altaf
- François Cauchy
Institutions
- University of Verona (IT)
- The University of Sydney (AU)
- Cleveland Clinic (US)
- University of Ottawa (CA)
- Second Military Medical University (CN)
- Keio University (JP)
- Hôpital Beaujon (FR)
- The Ohio State University Wexner Medical Center (US)
- Westmead Hospital (AU)
- IRCCS Ospedale San Raffaele (IT)
- Hospital Curry Cabral (PT)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Institutul Clinic Fundeni (RO)
- Yokohama City University (JP)
- University of Colorado Denver (US)
- Stanford University (US)
Publication Details
- Journal
- Annals of Surgery Open
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1097/as9.0000000000000557
- Citations
- 10
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 13.22