Cordycepin mediates pyroptosis in HCC through the upregulation of TXNIP and synergizes with anti–PD-L1 immunotherapy

Overall, our study successfully established a combined therapeutic strategy using COR and PD-L1 inhibitors. This strategy has significant synergistic effects on cancer cells, highlighting its importance in cancer therapy.

Authors

Institutions

Publication Details

Journal
Hepatology Communications
Published
2025-02-26
DOI
https://doi.org/10.1097/hc9.0000000000000633
Citations
6
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
6.91
Controls
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article

Cordycepin mediates pyroptosis in HCC through the upregulation of TXNIP and synergizes with anti–PD-L1 immunotherapy

Guo‐Huan Yang, Wen‐Zheng Qin, Wenxin Xu, Ai‐Wu Ke et al.
6 citations
Hepatology Communications
Endoplasmic Reticulum Stress and Disease
6.91
article

Cordycepin mediates pyroptosis in HCC through the upregulation of TXNIP and synergizes with anti–PD-L1 immunotherapy

Guo‐Huan Yang, Wen‐Zheng Qin, Wenxin Xu, Ai‐Wu Ke, Hui Shen, Chang‐Jun Tan, Bu-Gang Liang, Yi-Min Zheng
article en
6 citations

Abstract

Overall, our study successfully established a combined therapeutic strategy using COR and PD-L1 inhibitors. This strategy has significant synergistic effects on cancer cells, highlighting its importance in cancer therapy.

Hepatology CommunicationsVol. 9(3)
Fudan University (CN), Zhongshan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 3%
Endoplasmic Reticulum Stress and Disease
6.91
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