Reduced DNMT1 expression associated with TP53 promoter hypomethylation mediate enhanced granulosa cell senescence during ovarian aging
Decreased DNMT1 with hypomethylation of the CpG sites within the <i>P53</i> promoter CpG island in GCs is involved in ovarian aging.
Authors
- Shuhong Pan
- Sui‐Bing Miao (ORCID: https://orcid.org/0000-0001-5137-6823)
- Hui Guo (ORCID: https://orcid.org/0000-0003-3901-6336)
- Jian Zhao (ORCID: https://orcid.org/0000-0003-0676-4960)
- Cai-Ping Geng
- Dexian Kong (ORCID: https://orcid.org/0000-0003-3693-2443)
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
- Institute of Reproductive Medicine (IN)
Publication Details
- Journal
- Gynecological Endocrinology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1080/09513590.2025.2471549
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61