Antiretroviral drug exposure in pregnancy and risk of congenital anomalies: a European case/non-case malformed study

Our study does not reveal new signals but confirms the previously identified signal between congenital heart defects and fetal exposure to zidovudine. The physio-pathological hypothesis induced by zidovudine exposure should be explored in future studies.

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Publication Details

Journal
European Journal of Clinical Pharmacology
Published
2025-02-26
DOI
https://doi.org/10.1007/s00228-025-03814-w
Citations
1
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
1.40

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article

Antiretroviral drug exposure in pregnancy and risk of congenital anomalies: a European case/non-case malformed study

Anna‐Belle Beau, Anke Rißmann, Maria A. Loane, Helen Dolk et al.
1 citations
European Journal of Clinical Pharmacology
HIV/AIDS Research and Interventions
1.40
article

Antiretroviral drug exposure in pregnancy and risk of congenital anomalies: a European case/non-case malformed study

Anna‐Belle Beau, Anke Rißmann, Maria A. Loane, Helen Dolk, Christine Damase‐Michel, David Tucker, Clara Cavero‐Carbonell, Isabelle Perthus, Anna Latos‐Bieleńska, Ester Garne, Vera Nelen, Anna Pierini, Laura Saint‐Lary, Florence Rouget, Valériane Leroy, Agnès Sommet, Mary O’Mahony, Joanna Sichitiu, Isabelle Monier, Amanda J. Neville, Jonathan Hoareau
article en
1 citations

Abstract

Our study does not reveal new signals but confirms the previously identified signal between congenital heart defects and fetal exposure to zidovudine. The physio-pathological hypothesis induced by zidovudine exposure should be explored in future studies.

European Journal of Clinical PharmacologyVol. 81(5)
Poznan University of Medical Sciences (PL), Université Toulouse III - Paul Sabatier (FR), University of Ulster (GB), Inserm (FR), Université Fédérale de Toulouse Midi-Pyrénées (FR), University of Ferrara (IT), Singleton Hospital (GB), Centre Hospitalier Universitaire Vaudois (CH), Centre Hospitalier Universitaire de Toulouse (FR), Health Service Executive (IE), Public Health Wales (GB), Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (ES), Istituto di Fisiologia Clinica (IT), Institut de Recherche en Santé, Environnement et Travail (FR), Centre Hospitalier Universitaire de Clermont-Ferrand (FR), Lillebaelt Hospital (DK), National Research Council (IT), Centre Hospitalier Universitaire de Rennes (FR), Université de Rennes (FR), Otto-von-Guericke-Universität Magdeburg (DE)
Agence Nationale de Recherches sur le Sida et les Hépatites Virales, Université de Toulouse
Good health and well-being
Openalex Percentile: Top 24%
HIV/AIDS Research and Interventions
1.40
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