Causal Association Between Inflammatory Proteins, Inflammatory Cells, and Cauda Equina Syndrome: A Two-Sample Mendelian Randomization
Our findings extend genetic research to causal analysis between inflammatory proteins, cells, and CES. We found 2 proteins and 12 cells as risk factors and 2 proteins and 7 cells as protective factors. Further investigations are needed to verify whether these inflammation markers can be used to prevent or treat CES.
Authors
- Xiaofei Sun (ORCID: https://orcid.org/0000-0003-1675-5523)
- Jinyu Wang
- Jianpeng Xing
- Kaiqiang Sun (ORCID: https://orcid.org/0000-0002-0272-8383)
- Jiangang Shi (ORCID: https://orcid.org/0000-0003-2133-0108)
- Yuan Wang (ORCID: https://orcid.org/0000-0001-5252-3215)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-7347-0367)
- Qing‐Jie Kong (ORCID: https://orcid.org/0000-0002-3788-305X)
- Linhui Han
Institutions
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.wneu.2025.123826
- Citations
- 1
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Second Military Medical University
- Shanghai Shenkang Hospital Development Center