Association of peripheral CD8<sup>+</sup> T cell activation with disease activity and treatment resistance in systemic lupus erythematosus
In SLE, greater proportions of highly cytotoxic and proinflammatory activated CD8<sup>+</sup> T cells in peripheral blood-modulated disease activity, organ damage and residual treatment resistance, presenting a potential treatment target.
Authors
- Yusuke Miyazaki (ORCID: https://orcid.org/0000-0001-5692-3881)
- Yuya Fujita (ORCID: https://orcid.org/0000-0003-4163-9356)
- Yoshiya Tanaka (ORCID: https://orcid.org/0000-0002-0807-7139)
- Satoshi Kubo (ORCID: https://orcid.org/0000-0001-9693-9263)
- Shingo Nakayamada (ORCID: https://orcid.org/0000-0002-2209-8454)
- Koshiro Sonomoto (ORCID: https://orcid.org/0000-0002-4003-8842)
- Hiroaki Tanaka (ORCID: https://orcid.org/0000-0001-8814-740X)
Institutions
- University of Occupational and Environmental Health Japan (JP)
Publication Details
- Journal
- RMD Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/rmdopen-2024-005122
- Citations
- 5
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- University of Occupational and Environmental Health
- Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare