Dementia Medications and Their Association with Pain Medication Use in Medicare Beneficiaries with Alzheimer’s Disease/Alzheimer’s Disease-Related Dementias and Chronic Pain
Older adults with co-occurring AD/ADRD and chronic pain who were on dementia medications had lower odds of being prescribed opioid analgesics. Memantine and ACHEIs should be explored as potential opioid-sparing medications for older adults with AD/ADRD, given their relatively safe profiles. Future studies are needed to examine repurposing dementia medications for pain treatment.
Authors
- Brian Downer (ORCID: https://orcid.org/0000-0001-5792-0527)
- Jordan Westra (ORCID: https://orcid.org/0000-0002-1473-1766)
- Sadaf Arefi Milani (ORCID: https://orcid.org/0000-0001-6631-6532)
- Yong Fang Kuo
- Mukaila A. Raji
Institutions
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- Drugs & Aging
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1007/s40266-025-01181-w
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging
- National Institute on Drug Abuse