USP2 reversed cisplatin resistance through p53-mediated ferroptosis in NSCLC
USP2 acted on the K305R site of p53, which resulted in its deubiquitination. This cellular process could modulate cisplatin resistance through ferroptosis in NSCLC. This study could provide a potential therapeutic target to NSCLC.
Authors
- Ruichao Li (ORCID: https://orcid.org/0000-0001-8333-9891)
- Rui Zhang (ORCID: https://orcid.org/0000-0002-6147-1573)
- Jia Li (ORCID: https://orcid.org/0000-0002-2286-1704)
- Yanmei Gong
Institutions
- Yuncheng University (CN)
- Shanxi Medical University (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1186/s12920-025-02108-5
- Citations
- 8
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 12.15