Efficacy of integrated social cognitive remediation vs neurocognitive remediation in schizophrenia: Results from the multicenter randomized controlled ISST (Integrated Social Cognition And Social Skills Therapy) study
Both therapies differentially improved measures of the cognitive domains they were designed for. Moreover, they both improved social functioning with high effect sizes (d = 0.8-1.0), underlining the important role of CRT in recovery-oriented schizophrenia treatment. However, the absence of a third group without an active intervention limits the interpretability of the results.
Authors
- Andreas Meyer‐Lindenberg (ORCID: https://orcid.org/0000-0001-5619-1123)
- Karolina Leopold (ORCID: https://orcid.org/0000-0003-3445-1611)
- Wolfgang Wölwer (ORCID: https://orcid.org/0000-0001-7642-6778)
- René Hurlemann (ORCID: https://orcid.org/0000-0003-2628-565X)
- Anke Brockhaus‐Dumke (ORCID: https://orcid.org/0000-0001-5285-7549)
- Daniel Kamp
- Kerstin Daniela Rosenberger (ORCID: https://orcid.org/0000-0003-3459-3812)
- Karolin Weide
- Ana Muthesius
- Martin Hellmich (ORCID: https://orcid.org/0000-0001-5174-928X)
- Stefan Klingberg (ORCID: https://orcid.org/0000-0001-8081-7181)
- Mathias Riesbeck
- Sven Wasserthal (ORCID: https://orcid.org/0000-0003-2956-2472)
- Agnes Lowe
- Lea Hölz
- Joseph Kambeitz (ORCID: https://orcid.org/0000-0002-8988-3959)
- Andreas Bechdolf (ORCID: https://orcid.org/0000-0003-4796-3392)
- Bettina Klos
- Sabine Sadura
Institutions
- University of Cologne (DE)
- University Hospital Bonn (DE)
- Düsseldorf University Hospital (DE)
- Central Institute of Mental Health (DE)
- Vivantes Klinikum (DE)
- LVR-Klinik Bonn (DE)
- Rheinhessen-Fachklinik Mainz (DE)
- Klinikum im Friedrichshain (DE)
- University Hospital Cologne (DE)
- University Hospital Carl Gustav Carus (DE)
- Heinrich Heine University Düsseldorf (DE)
- Charité - Universitätsmedizin Berlin (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.schres.2025.02.015
- Citations
- 3
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Bundesministerium für Bildung und Forschung