Xiaoqinglong Decoction Attenuates Inflammatory Response and Mitochondrial Injury by Regulating the MyD88/NF-κB Pathway Dependent of TLR4 in Allergic Rhinitis
Inflammatory response and mitochondrial injury and the related MyD88/NF-κB signaling pathway play crucial roles in AR. XQLD supplementation inhibits AR-induced inflammation and mitochondrial injury by regulating TLR4 expression and TLR4-mediated MyD88/NF-κB pathway activation, thereby facilitating the therapeutic effect.
Authors
- Xiaofu Zhai
- Yao Sun (ORCID: https://orcid.org/0000-0002-4391-377X)
- Chengfei Zhang (ORCID: https://orcid.org/0000-0002-6016-9436)
- Lirong Wang (ORCID: https://orcid.org/0000-0002-2446-0656)
- Qi Yang (ORCID: https://orcid.org/0000-0002-2963-7983)
- Kunmin Wu
- J.G. An (ORCID: https://orcid.org/0000-0002-7473-9663)
- Yongjun Wu
- Y. Fei
Institutions
- Nanjing University of Chinese Medicine (CN)
- National Quality Inspection and Testing Center for Surveying and Mapping Products (CN)
- Nanjing Product Quality Supervision and Inspection Institute (CN)
- Jiangsu Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1159/000544768
- Citations
- 3
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 2.39