Glycoprotein acetyls response to a mixed meal is associated with increased insulin resistance and risk of type 2 diabetes in a middle-aged population
In this middle-aged population with overweight, those with a high GlycA meal response, including those with low fasting GlycA, had an increased risk of diabetes. A high inflammatory meal response shows promise to identify other people at risk of T2D than fasting levels alone. This risk group may benefit from prevention by precision nutrition to reduce the inflammatory meal response.
Authors
- Jeroen H. P. M. van der Velde (ORCID: https://orcid.org/0000-0002-2904-4598)
- Raymond Noordam (ORCID: https://orcid.org/0000-0001-7801-809X)
- Frits R. Rosendaal (ORCID: https://orcid.org/0000-0003-2558-7496)
- Dennis O. Mook‐Kanamori (ORCID: https://orcid.org/0000-0002-0182-5122)
- Eelco J.P. de Koning (ORCID: https://orcid.org/0000-0002-1232-7022)
- Rory C. Monahan (ORCID: https://orcid.org/0000-0003-2561-7085)
- Ruifang Li‐Gao (ORCID: https://orcid.org/0000-0003-0650-1351)
- Saskia le Cessie (ORCID: https://orcid.org/0000-0003-2154-4923)
- Ko Willems van Dijk (ORCID: https://orcid.org/0000-0002-2172-7394)
- Renée de Mutsert (ORCID: https://orcid.org/0000-0002-5470-0673)
Institutions
- Loyola University Medical Center (US)
- Leiden University Medical Center (NL)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.clnesp.2025.02.013
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16