Determining kidney function-specific thresholds for N-terminal pro-B-type natriuretic peptide in heart failure risk prediction among patients with chronic kidney disease: a multicentre, observational, cohort study
In patients with CKD, NT-proBNP levels must be interpreted in the context of kidney function, as eGFR-specific thresholds provide superior HF risk stratification. These findings support adopting kidney function-adjusted thresholds rather than a uniform cut-off to improve HF risk prediction.
Authors
- Shiyu Zhou (ORCID: https://orcid.org/0000-0002-5902-8812)
- Junzhe Chen (ORCID: https://orcid.org/0009-0005-7573-0707)
- Sheng Nie (ORCID: https://orcid.org/0000-0002-8267-7909)
- Yi Lu (ORCID: https://orcid.org/0000-0002-7348-8903)
- Yuxin Luo (ORCID: https://orcid.org/0000-0002-8078-4786)
- Andrew Fanuel Lukwaro
- Ying Tang (ORCID: https://orcid.org/0000-0002-2027-5955)
- Ruixuan Chen (ORCID: https://orcid.org/0000-0002-2925-9484)
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Heart
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1136/heartjnl-2024-324679
- Citations
- 2
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province