Assessing the clinical applicability of dimensionality reduction algorithms in flow cytometry for hematologic malignancies
This study shows that DR-based gating streamlines data interpretation and minimizes overlooked populations, demonstrating significant potential as a valuable tool in MFC analysis for hematologic malignancies.
Authors
- Jong Kwon Lee (ORCID: https://orcid.org/0000-0002-6230-1242)
- Chul Won Jung (ORCID: https://orcid.org/0000-0002-5474-6807)
- Hee Young Ju (ORCID: https://orcid.org/0000-0001-6744-0412)
- Keon Hee Yoo (ORCID: https://orcid.org/0000-0002-5980-7912)
- Min‐Seung Park (ORCID: https://orcid.org/0000-0002-4482-3098)
- Boram Kim (ORCID: https://orcid.org/0000-0001-5695-8902)
- Hee‐Jin Kim (ORCID: https://orcid.org/0000-0003-3741-4613)
- Hyun‐Young Kim (ORCID: https://orcid.org/0000-0003-0553-7096)
Institutions
- Samsung Medical Center (KR)
- Kangbuk Samsung Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1515/cclm-2025-0017
- Citations
- 5
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Research Foundation of Korea