Glucagon-Like Peptide 1 Receptor (Glp1r) Deficiency Does Not Appreciably Alter Airway Inflammation or Gut-Lung Microbiome Axis in a Mouse Model of Obese Allergic Airways Disease and Bariatric Surgery
Herein, GLP-1R deficiency had surprisingly little effect on host gut and lung microbiomes and health, despite recent studies suggesting that GLP-1 receptor agonists are protective against lung inflammation.
Authors
- Claudia K. Gunsch (ORCID: https://orcid.org/0000-0002-8555-0313)
- Jennifer L. Ingram (ORCID: https://orcid.org/0000-0002-5269-8864)
- Jack T. Womble (ORCID: https://orcid.org/0000-0001-8194-5038)
- Joshua A. Granek (ORCID: https://orcid.org/0000-0003-3908-5016)
- Yeon Ji Kim (ORCID: https://orcid.org/0000-0002-1118-5026)
- Pixu Shi (ORCID: https://orcid.org/0000-0002-2455-2622)
- Mark D. Ihrie (ORCID: https://orcid.org/0000-0001-8638-5869)
- A Meares
- Victoria M Ihrie
Institutions
- Duke University (US)
- Duke Medical Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Journal of Asthma and Allergy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jaa.s478329
- Citations
- 1
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- National Science Foundation
- National Institutes of Health
- School of Medicine, Duke University
- National Heart, Lung, and Blood Institute