Role of Characteristic Pulmonary Impedance With Exercise for Detection of Abnormal Pulmonary Vascular Response and Uncoupling in Pulmonary Hypertension Resulting From Heart Failure With Preserved Ejection Fraction
Despite the small sample size, RV-PA uncoupling with exercise was significantly negatively correlated with Z<sub>C</sub> in PH-HFpEF, which was not evident in precapillary PH, suggesting that abnormal exercise pulsatile hemodynamics may be key to RV failure in left-sided heart disease.
Authors
- Mitchel J. Colebank (ORCID: https://orcid.org/0000-0002-2294-9124)
- Christopher Lechuga
- Aimee Teo Broman (ORCID: https://orcid.org/0000-0003-3783-2807)
- Claudia E. Korcarz (ORCID: https://orcid.org/0000-0001-9691-9027)
- Naomi C. Chesler (ORCID: https://orcid.org/0000-0002-7612-5796)
- Farhan Raza (ORCID: https://orcid.org/0000-0001-5750-2034)
- Jens C. Eickhoff (ORCID: https://orcid.org/0000-0003-0525-6462)
Institutions
- University of Wisconsin–Madison (US)
- Edwards Lifesciences (United States) (US)
Publication Details
- Journal
- CHEST Journal
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.chest.2025.02.019
- Citations
- 5
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- American Heart Association
- University of Wisconsin-Madison
- Alabama Humanities Alliance
- National Institutes of Health
- Institute for Clinical and Translational Research, University of Wisconsin, Madison
- School of Medicine and Public Health, University of Wisconsin-Madison
- National Heart, Lung, and Blood Institute
- National Center for Research Resources
- National Center for Advancing Translational Sciences