Comparison of radiobiological effects induced by radiolabeled antibodies in human cancer cells and fungal cells
While both cell lines showed similar responses to <sup>225</sup>Ac- and <sup>177</sup>Lu-enabled RIT, variations were observed based on cellular structure, doubling times and DNA repair mechanisms. This study offers insights for future in vivo research on fungal infections in cancer setting.
Authors
- Connor Frank (ORCID: https://orcid.org/0000-0002-2910-9857)
- Ekaterina Dadachova (ORCID: https://orcid.org/0000-0001-7300-6479)
- Mackenzie E. Malo (ORCID: https://orcid.org/0000-0002-9118-0806)
- Jonathan Bonet Ramírez
- Kevin J. H. Allen (ORCID: https://orcid.org/0000-0001-7046-7317)
Institutions
- University of Saskatchewan (CA)
Publication Details
- Journal
- International Journal of Radiation Biology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1080/09553002.2025.2467691
- Citations
- 2
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72