“Chocolate Chip Sign” on Susceptibility-Weighted Imaging
The Chocolate Chip Sign on SWI represents a novel and promising neuroimaging biomarker for HRSVD. This finding holds significant potential for facilitating early diagnosis, prompting timely genetic testing, and appropriate family screening for this rare genetic disorder.
Authors
- Hironaka Igarashi (ORCID: https://orcid.org/0000-0003-1663-5564)
- Masahiro Uemura (ORCID: https://orcid.org/0000-0003-0645-0099)
- Akiyoshi Kakita (ORCID: https://orcid.org/0000-0003-4244-0277)
- Tomohiko Ishihara (ORCID: https://orcid.org/0000-0001-9915-8665)
- Sho Kitahara (ORCID: https://orcid.org/0009-0007-9899-9754)
- Shigeo Murayama (ORCID: https://orcid.org/0000-0001-9709-5242)
- Atchayaram Nalini (ORCID: https://orcid.org/0000-0001-9791-3639)
- Yuya Hatano (ORCID: https://orcid.org/0000-0001-9048-5985)
- Masaki Watanabe (ORCID: https://orcid.org/0000-0002-5236-7563)
- Taisuke Kato (ORCID: https://orcid.org/0000-0001-5696-7104)
- Rie Saito (ORCID: https://orcid.org/0000-0001-7294-5183)
- Osamu Onodera (ORCID: https://orcid.org/0000-0003-3354-5472)
- Shoichiro Ando (ORCID: https://orcid.org/0000-0002-5852-9893)
- Yosuke Ito (ORCID: https://orcid.org/0000-0003-0840-8214)
Institutions
- Tokyo Metropolitan Institute of Gerontology (JP)
- Nishi Niigata Chuo National Hospital (JP)
- National Institute of Mental Health and Neurosciences (IN)
- Niigata University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Neurology Genetics
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1212/nxg.0000000000200237
- Citations
- 6
- Primary Topic
- Medical Imaging and Pathology Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.59