Acoustic Cavitation Emissions Predict Near-complete/complete Histotripsy Treatment in Soft Tissues
Features measured from ACE-signals, particularly the lifespan-slope and percent reduction, were used to predict near-complete/complete ablation of large-volume histotripsy treatments in ex vivo bovine liver, kidney, and brain tissues with good accuracy. Tissue heterogeneities were observed to impact the histotripsy damage and corresponding ACE-signals, and thus the predication accuracy.
Authors
- Ellen Yeats (ORCID: https://orcid.org/0009-0009-5177-1060)
- Scott Haskell (ORCID: https://orcid.org/0000-0003-1752-7573)
- Jonathan R. Sukovich (ORCID: https://orcid.org/0000-0002-5650-991X)
- Tim Hall
- Jiaqi Shi (ORCID: https://orcid.org/0000-0003-4893-1587)
- Zhen Xu (ORCID: https://orcid.org/0000-0001-8328-5483)
- J. Brian Fowlkes (ORCID: https://orcid.org/0000-0002-4536-3919)
Institutions
- University of Michigan (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Ultrasound in Medicine & Biology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1016/j.ultrasmedbio.2025.02.005
- Citations
- 4
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.70
Funders
- Focused Ultrasound Foundation
- National Institutes of Health
- National Cancer Institute