Эффективность и профилактика осложнений использования биодеградируемого каркаса нового поколения - magmaris при остром инфаркте миокарда

Background. to evaluate the immediate clinical and angiographic success in patients with NSTEMI, who underwent percutaneous coronary intervention (PCI) with the installation of a new generation of resorbable scaffolds “Magmaris”. Materials and methods. Material and methods: clinical data of 64 patients with an acute form of coronary artery disease (49 men and 15 women) who were fitted with a biodegradable Magmaris frame were used. Anamnestic, general clinical, laboratory and coronary angiographic data were obtained from patients with acute forms of coronary artery disease who underwent percutaneous coronary intervention (PCI) with the installation of a Magmaris BVS frame as endovascular treatment. Results. Implantation of bioresorbable scaffolds "Magmaris"in patients with coronary artery disease was characterized by immediate good angiographic success in 100% of cases and clinical success in 95.8% of cases. Patients with low LVEF were characterized by a higher SYNTAX score (p<0.001), a greater number of multivessel lesions (p> 0.05), the involvement of a larger number of coronary basins (p> 0.05), and a greater number of stenotic segments per patient (p> 0.05) and, accordingly, a longer atherosclerotic lesion. This was confirmed by an inverse correlation (which did not reach the level of reliability), which may have been due to the small size of the sample under study. The presence of CKD, according to angiographic characteristics, was associated with a greater number of multivessel and complex (type "C"according to the ACC / ANA classification) lesions, a greater number of stenotic segments and, accordingly, the implantation of more devices, while the immediate angiographic success of the PCI procedure was 100%, but clinical success was 5.9% lower, than in patients without CKD. Comorbidity with type 2 diabetes, according to angiographic characteristics, was accompanied by a relatively longer and more severe type (type "C") of atherosclerotic lesions of the coronary arteries, despite the relatively lower incidence of multivessel lesions and a smaller number of stenotic segments. The presence of type 2 diabetes did not in any way affect the angiographic success of the PCI procedure (which was 100%), but worsened the clinical success by 11.1%. Conclusion. The primary results of evaluating the use of the bioresorbable scaffold "Magmaris"in our country turned out to be very encouraging. However, it is necessary to conduct further more in-depth studies in this direction, in particular, to study the issues of the influence of various risk factors or pathological conditions on angiographic characteristics and assess the safety and effectiveness of using the polymer scaffold "Magmaris".