Exploring the hepatic-ophthalmic axis through immune modulation and cellular dynamics in diabetic retinopathy and non-alcoholic fatty liver disease

The comprehensive investigation of T cells, macrophages, endothelial cells, and the CD45 signaling pathway advances our understanding of the intricate biological processes underpinning DR and NAFLD. This research underscores the imperative of exploring immune-related cell interactions, shedding light on novel therapeutic avenues in these disease contexts.

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Publication Details

Journal
Human Genomics
Published
2025-02-26
DOI
https://doi.org/10.1186/s40246-025-00730-z
Citations
2
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
3.63
Controls
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article

Exploring the hepatic-ophthalmic axis through immune modulation and cellular dynamics in diabetic retinopathy and non-alcoholic fatty liver disease

Yinjian Zhang, Jiajun Wu, Yibin Feng, Leilei Wang et al.
2 citations
Human Genomics
Diabetes and associated disorders
3.63
article

Exploring the hepatic-ophthalmic axis through immune modulation and cellular dynamics in diabetic retinopathy and non-alcoholic fatty liver disease

Yinjian Zhang, Jiajun Wu, Yibin Feng, Leilei Wang, Cheng Zhang, Shuyan Zhang
article en
2 citations

Abstract

The comprehensive investigation of T cells, macrophages, endothelial cells, and the CD45 signaling pathway advances our understanding of the intricate biological processes underpinning DR and NAFLD. This research underscores the imperative of exploring immune-related cell interactions, shedding light on novel therapeutic avenues in these disease contexts.

Human GenomicsVol. 19(1)
Shanghai Eye Disease Prevention & Treatment Center (CN), Shanghai University of Traditional Chinese Medicine (CN), Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN), University of Hong Kong (HK)
Good health and well-being
Openalex Percentile: Top 9%
Diabetes and associated disorders
3.63
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