Potential Role of ABCF2 Gene in Pudendal Nerve Neuropathy and Interstitial Cystitis
Although the precise role of <i>ABCF2</i> should be supported by further studies, we hypothesize that its disruption might impair ATP metabolism, likely altering the nociceptive response and leading to the patient's neuropathy. Further analyses are imperative to validate this research, for laying the groundwork for a specific therapy targeting the genetic dysregulation involved in this condition.
Authors
- Giuseppe Bruno (ORCID: https://orcid.org/0000-0001-6948-7169)
- Antonino Musumeci (ORCID: https://orcid.org/0000-0002-8999-3365)
- Mirella Vinci (ORCID: https://orcid.org/0000-0003-3026-8510)
- Giordana Tinnirello (ORCID: https://orcid.org/0009-0005-2680-1804)
- Daniele Porru (ORCID: https://orcid.org/0000-0002-8502-6669)
- Concetta Federico (ORCID: https://orcid.org/0000-0002-0160-9040)
- Salvatore Saccone (ORCID: https://orcid.org/0000-0001-7568-5823)
- Alda Ragalmuto (ORCID: https://orcid.org/0000-0002-7399-964X)
- Simone Treccarichi (ORCID: https://orcid.org/0000-0001-5631-9991)
- Francesco Calı̀ (ORCID: https://orcid.org/0000-0001-8667-8223)
- Jessica Farina (ORCID: https://orcid.org/0000-0002-5101-7836)
Institutions
- University of Catania (IT)
- Oasi Maria SS (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Genes
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3390/genes16030281
- Citations
- 2
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 3.67