HOXA5 Derives the Malignant Progression and Cisplatin Resistance of Esophageal Squamous Cell Carcinoma by Regulating USP18‐Mediated IFI27 Deubiquitination
USP18 transcriptionally mediated by HOXA5 could promote cell malignant behaviors and DDP resistance through deubiquitinating IFI27, providing a promising therapeutic target for ESCC treatment.
Authors
- Xiang‐Yan Liu (ORCID: https://orcid.org/0000-0002-6998-1543)
- Pan Zheng (ORCID: https://orcid.org/0000-0002-6067-626X)
- Qiang Wang (ORCID: https://orcid.org/0000-0003-1935-2631)
- Yuxin Chen (ORCID: https://orcid.org/0000-0002-4709-8151)
- Shiheng Ren (ORCID: https://orcid.org/0009-0001-9051-750X)
Institutions
- Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/1759-7714.70013
- Citations
- 3
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Natural Science Foundation of Shandong Province