Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS)

High rates of treatment discontinuation and subsequent restart were observed across all subgroups, implying fluctuating sMRA use. However, heightened cardiovascular risk may decrease the odds of discontinuation.

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Publication Details

Journal
Pragmatic and Observational Research
Published
2025-02-01
DOI
https://doi.org/10.2147/por.s489791
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00

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article

Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS)

Alain Gay, Vincent J. Willey, Elena Pessina, Charlie Scott et al.
Pragmatic and Observational Research
Hormonal Regulation and Hypertension
article

Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS)

Alain Gay, Vincent J. Willey, Elena Pessina, Charlie Scott, Nihar R. Desai, Nikolaus G. Oberprieler, Kerstin Folkerts, Rakesh K. Singh, Emma Richard, Chia‐Chen Teng
article en

Abstract

High rates of treatment discontinuation and subsequent restart were observed across all subgroups, implying fluctuating sMRA use. However, heightened cardiovascular risk may decrease the odds of discontinuation.

Pragmatic and Observational ResearchVol. Volume 16
Clarion University (US), Bayer (Norway) (NO), Bayer (United States) (US), Eli Lilly (United States) (US), Yale University (US), Bayer (Italy) (IT), Health Economics and Outcomes Research (United Kingdom) (GB), Bayer (Germany) (DE)
Bayer
Openalex Percentile: Top 95%
Hormonal Regulation and Hypertension
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Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS) — Alain Gay, Vincent J. Willey, et al. · Pragmatic and Observational Research (2025) | TGRS Research Map | TGRS