Enhancement of Attachment of Biomolecules on the Surface of a Blood Vessel Microchip Under High Blood Flow Rates

This paper reports on a new assay to enhance the immobilization of biomolecules on the surface of a blood vessel microchip, which will render the significantly improved binding of the biomolecules to the surface of the microfluidic channels, thereby allowing the studies of the behaviors of the biomolecules such as platelets under a broad range of flowing shear stresses from normal physiological to extreme pathological conditions.