Pulmonary artery stenting for palliative treatment of refractory hypoxaemia in a patient with small cell lung cancer

Pulmonary artery stenosis (PAS) is most encountered in the paediatric population as a congenital anomaly. In adults, PAS from extrinsic compression of the pulmonary artery (PA) results from conditions such as fibrosing mediastinitis, malignancy, infections and anastomotic stenosis after lung transplantation. We describe a woman in her 50s with extensive stage small cell lung cancer who presented with symptoms of shortness of breath and hypoxaemic respiratory failure. CT angiography chest showed a progressively enlarging mediastinal mass causing severe compressive stenosis of the right PA and moderate stenosis of the left PA. Her symptoms did not improve despite using bronchodilators and intravenous steroids. Pulmonary angiography confirmed clinically significant stenosis of her right PA. The placement of a single stent within the right PA provided significant improvement in symptoms and supplemental oxygen requirement within 24 hours.

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Publication Details

Journal
BMJ Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1136/bcr-2024-264580
Primary Topic
Vascular Anomalies and Treatments
Type
article
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article

Pulmonary artery stenting for palliative treatment of refractory hypoxaemia in a patient with small cell lung cancer

Aneeqa Yousaf Dar, Katherine Smith, Mian Harris Iftikhar, Raj Parikh
BMJ Case Reports
Vascular Anomalies and Treatments
article

Pulmonary artery stenting for palliative treatment of refractory hypoxaemia in a patient with small cell lung cancer

Aneeqa Yousaf Dar, Katherine Smith, Mian Harris Iftikhar, Raj Parikh
article en

Abstract

Pulmonary artery stenosis (PAS) is most encountered in the paediatric population as a congenital anomaly. In adults, PAS from extrinsic compression of the pulmonary artery (PA) results from conditions such as fibrosing mediastinitis, malignancy, infections and anastomotic stenosis after lung transplantation. We describe a woman in her 50s with extensive stage small cell lung cancer who presented with symptoms of shortness of breath and hypoxaemic respiratory failure. CT angiography chest showed a progressively enlarging mediastinal mass causing severe compressive stenosis of the right PA and moderate stenosis of the left PA. Her symptoms did not improve despite using bronchodilators and intravenous steroids. Pulmonary angiography confirmed clinically significant stenosis of her right PA. The placement of a single stent within the right PA provided significant improvement in symptoms and supplemental oxygen requirement within 24 hours.

BMJ Case ReportsVol. 18(2)
Hartford Hospital (US), St. Francis Hospital (US), UConn Health (US), Michigan State University (US)
Good health and well-being
Openalex Percentile: Top 95%
Vascular Anomalies and Treatments
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Pulmonary artery stenting for palliative treatment of refractory hypoxaemia in a patient with small cell lung cancer — Aneeqa Yousaf Dar, Katherine Smith, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS