Laryngeal squamous cell carcinoma disguised as asthma

Head and neck squamous cell carcinoma (HNSCC) with laryngeal involvement can lead to significant airway obstruction and compromise. This case report details a female patient in her 60s with a history of asthma who presented with refractory dyspnoea and persistent hoarseness, initially attributed to asthma. After multiple emergency room visits and treatment with bronchodilators and steroids, further investigation revealed an exophytic mass in the larynx, diagnosed as SCC. Despite normal pulmonary function tests, imaging indicated significant airway narrowing. The patient underwent a tracheostomy to secure her airway and was subsequently referred for curative surgery. This case underscores the importance of considering HNSCC in patients with unexplained respiratory symptoms, regardless of smoking history, and highlights the need for thorough investigation to prevent complications from advanced disease. Early multidisciplinary intervention is crucial in managing such cases effectively.

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Publication Details

Journal
BMJ Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1136/bcr-2024-264064
Primary Topic
Tracheal and airway disorders
Type
article
Field-Weighted Citation Impact
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article

Laryngeal squamous cell carcinoma disguised as asthma

Pramod Reddy, Kabeer Ali, Jason Corcoran, Ty J Merry
BMJ Case Reports
Tracheal and airway disorders
article

Laryngeal squamous cell carcinoma disguised as asthma

Pramod Reddy, Kabeer Ali, Jason Corcoran, Ty J Merry
article en

Abstract

Head and neck squamous cell carcinoma (HNSCC) with laryngeal involvement can lead to significant airway obstruction and compromise. This case report details a female patient in her 60s with a history of asthma who presented with refractory dyspnoea and persistent hoarseness, initially attributed to asthma. After multiple emergency room visits and treatment with bronchodilators and steroids, further investigation revealed an exophytic mass in the larynx, diagnosed as SCC. Despite normal pulmonary function tests, imaging indicated significant airway narrowing. The patient underwent a tracheostomy to secure her airway and was subsequently referred for curative surgery. This case underscores the importance of considering HNSCC in patients with unexplained respiratory symptoms, regardless of smoking history, and highlights the need for thorough investigation to prevent complications from advanced disease. Early multidisciplinary intervention is crucial in managing such cases effectively.

BMJ Case ReportsVol. 18(2)
Alabama College of Osteopathic Medicine (US), University of Florida (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 95%
Tracheal and airway disorders
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Laryngeal squamous cell carcinoma disguised as asthma — Pramod Reddy, Kabeer Ali, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS