Plasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections

Plasma mcfDNA sequencing offers a rapid, noninvasive method of detecting K. kingae causing pediatric spinal infections. This culture-independent approach may facilitate diagnosis, despite antibiotic pretreatment and subsequently targeted therapy and potentially obviate the need for biopsy.

Authors

Institutions

Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-02-21
DOI
https://doi.org/10.1097/inf.0000000000004743
Citations
5
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
10.03
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Plasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections

Audrey R. Lloyd, Manuel R. Cotilla, Asim A. Ahmed, Catherine Foster et al.
5 citations
The Pediatric Infectious Disease Journal
Orthopedic Infections and Treatments
10.03
article

Plasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections

Audrey R. Lloyd, Manuel R. Cotilla, Asim A. Ahmed, Catherine Foster, Pablo Marcelo Laufer, John Arnold, Nazia Kabani, Sarah Y. Park, David W. Kimberlin, Pablo Yagupsky, Ana Del Valle Penella, Carolina Sanchez‐Vegas, Marian E. Melish, Alejandro Jordán-Villegas, Adriana Sarmiento Clemente, Connie Trieu, Matthew Smollin, Martin Lindner, L. E. R. Patterson, Joshua Cooper
article en
5 citations

Abstract

Plasma mcfDNA sequencing offers a rapid, noninvasive method of detecting K. kingae causing pediatric spinal infections. This culture-independent approach may facilitate diagnosis, despite antibiotic pretreatment and subsequently targeted therapy and potentially obviate the need for biopsy.

The Pediatric Infectious Disease JournalVol. 44(6)
Ben-Gurion University of the Negev (IL), Boston Children's Hospital (US), Arkansas Children's Hospital (US), Baylor College of Medicine (US), Kapiolani Medical Center for Women and Children (US), Soroka Medical Center (IL), Arnold Palmer Hospital for Children (US), University of Alabama at Birmingham (US), University of Florida (US), Rady Children's Hospital-San Diego (US), East Tennessee Children's Hospital (US), Miami Children's Hospital (US), Texas Children's Hospital (US)
Good health and well-being
Openalex Percentile: Top 2%
Orthopedic Infections and Treatments
10.03
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.